Comments on: Mixed Feelings on Inhalable Insulin

By: MJ

MJ — Mon, 23 Aug 2010 21:35:44 +0000

I’d be interested to learn more about the faster-acting part of this. Could be to the diabetic community what the emergency antihistimine injection is to allergies.

By: Taylor

Taylor — Tue, 17 Nov 2009 04:52:31 +0000

A pretty informative post overall, but why all the negative feedback. As a teenager with atypical diabetes, the kind where even my endocrinoligists is wary of putting in the type 1 or 2 category, inhalable insulin would be a godsend. I’ve given insulin injections to my grandmother for a while now, and when I was diagnosed gave them to myself. Not fun. I’m not taking insulin now, but the rigorous diet and excercise routine I need to manage my glucose levels is impossible for an active teen. I’m not sure if inhalable insulin is worth the trouble now, but I certainly hope research doesn’t end because it isn’t marketable.

By: Treatment Guidelines Elevated Cholesterol-A New Guide | Total Personal Health Care

Thu, 22 Oct 2009 02:25:39 +0000

[...] Mixed Feelings on Inhalable Insulin (diabetesmine.com) [...]

By: Grand Rounds: Brain and Cognition edition | SharpBrains

Grand Rounds: Brain and Cognition edition | SharpBrains — Tue, 20 Oct 2009 07:03:16 +0000

[...] Diabetes Mine wonders about the safety of inhalable insulin. [...]

By: olga

olga — Fri, 16 Oct 2009 05:02:10 +0000

two points, all pointing to thanks, but no thanks (dosage control!)

1. a while ago i worked at a biotech, and one of the guys in business dev was ALL OVER inhalable insulin. he would drag me over for a coffee, his eyes all googley, and go on about how great it would be to no longer have to take shots. not a PWD, surprise! i tried to explain how that’s not the tricky part…

2. i’m on a team investigating how “high-risk medications” are handled in a pediatric hospital. of the five drug categories, insulin is one. i certainly would not recommend something as imprecise as an inhalable delivery, for kids or adults.

time for my basal dose! (heck, today’s short needles are a dream compared to what they had 26 years ago!)

By: Ethan

Ethan — Thu, 15 Oct 2009 11:06:34 +0000

Thanks for Exubera,s image. I inform that the Insulin from outside the body is not an adequate treatment . Type 1 diabetics who would rather die than take their insulin injections

By: Clare

Clare — Thu, 15 Oct 2009 00:04:38 +0000

The alveoli were designed for the exchange of oxygen and carbon dioxide, not for insulin uptake. No thank you MannKind.

By: Rodney

Rodney — Tue, 13 Oct 2009 21:04:53 +0000

I was on one of the inhaled insulin trials a fews years ago (’02?) in Dallas. My biggest issue was the amount of control. You had 2 dose sizes to choose from. You either had to do a couple of the smaller ones or one of the larger ones, and nearly every time I used it, I would go low. It was a clunky machine to operate and there would always be some residue left over after you inhaled, so I don’t know how it could be as controlled as even being able to dial up half-units on the new pens.
The study I was in was focused on the ‘long-term’ effects but they were only testing lung capacity, before-during-and post use, rather than any MRI’s or lung/cancer effects. I think it ran about 6 months.
I would be concerned about offering this product to a senior. The lows seemed (at least to me) to hit rather quick and harsh. I can’t rate any of the newer delivery methods as it was a number of years ago that I was involved.

By: mcityrk

mcityrk — Tue, 13 Oct 2009 19:36:20 +0000

Hi Amy-

Speaking of David Kliff, any recent commentary from him on when a final decision on Amlyin’s once a week Byetta is due from the FDA Thanks-

By: saramy

saramy — Mon, 12 Oct 2009 22:36:48 +0000

Putting aside all the issues of potential lung problems and all the other issues, I can only imagine the taste would be kind of icky! I know that’s probably a small issue for most people, but not for me. I’m happy with my pump and my CGM.