Comments on: Lettuce Hope. But Not Too Much. http://www.diabetesmine.com/2007/09/lettuce-hope-bu.html A gold mine of straight talk and encouragement for people living with diabetes Mon, 13 Feb 2012 01:28:10 +0000 hourly 1 http://wordpress.org/?v= By: Greg http://www.diabetesmine.com/2007/09/lettuce-hope-bu.html/comment-page-1#comment-80738 Greg Sat, 27 Sep 2008 22:54:19 +0000 http://diabetesmine.dreamhosters.com/2007/09/11/lettuce-hope-but-not-too-much/#comment-80738 As I looked into the reports I at first was skeptical. I don’t care to have another delivery method for insulin since (as another comment pointed out) insulin is not a cure, but is only a temporary relief. But upon closer look, this technique with Lettuce is not to deliver insulin but is to stop the destruction of beta cells. See the following article: http://www.healthcentral.com/diabetes/c/5068/11951/lettuce-diabetes/ In this article you see that what is happening is that they are using a trick to get the intestinal cells to take up intact proinsulin, not insulin itself. This proinsulin does not affect the blood sugar; instead it results in a significant increase in compounds that suppress immune responses. This causes a reduction in the immune system attack on the beta cells. Over time the body replaces beta cells and they are not destroyed, so this is a potential cure of type 1 diabetes. I would be very excited to take part in a trial to see if this has benefit. It may be that this pill would have to be taken the rest of my life to continue to prevent the destruction of beta cells, but that is better than taking insulin (and symlin) through pumps and injections to treat some of the issues of not having beta cells. Greg As I looked into the reports I at first was skeptical. I don’t care to have another delivery method for insulin since (as another comment pointed out) insulin is not a cure, but is only a temporary relief. But upon closer look, this technique with Lettuce is not to deliver insulin but is to stop the destruction of beta cells. See the following article:

http://www.healthcentral.com/diabetes/c/5068/11951/lettuce-diabetes/

In this article you see that what is happening is that they are using a trick to get the intestinal cells to take up intact proinsulin, not insulin itself. This proinsulin does not affect the blood sugar; instead it results in a significant increase in compounds that suppress immune responses. This causes a reduction in the immune system attack on the beta cells. Over time the body replaces beta cells and they are not destroyed, so this is a potential cure of type 1 diabetes. I would be very excited to take part in a trial to see if this has benefit. It may be that this pill would have to be taken the rest of my life to continue to prevent the destruction of beta cells, but that is better than taking insulin (and symlin) through pumps and injections to treat some of the issues of not having beta cells.

Greg

]]> By: Ken http://www.diabetesmine.com/2007/09/lettuce-hope-bu.html/comment-page-1#comment-56072 Ken Thu, 28 Aug 2008 10:33:15 +0000 http://diabetesmine.dreamhosters.com/2007/09/11/lettuce-hope-but-not-too-much/#comment-56072 Since diabetes is an autoimmune disease any agent that acts to produce insulin producing cells in the pancreas will also be fought off by the body which will probably produce unanticipated side effects. Were probably still a long way off on this one. Since diabetes is an autoimmune disease any agent that acts to produce insulin producing cells in the pancreas will also be fought off by the body which will probably produce unanticipated side effects. Were probably still a long way off on this one.

]]> By: mel http://www.diabetesmine.com/2007/09/lettuce-hope-bu.html/comment-page-1#comment-38591 mel Tue, 06 Nov 2007 22:58:39 +0000 http://diabetesmine.dreamhosters.com/2007/09/11/lettuce-hope-but-not-too-much/#comment-38591 what about the chili peper extract cure from Canada last December? Any new info on that? I think Diabetes will be cured by something very simple- something right under our noses what about the chili peper extract cure from Canada last December? Any new info on that? I think Diabetes will be cured by something very simple- something right under our noses

]]> By: AmyT http://www.diabetesmine.com/2007/09/lettuce-hope-bu.html/comment-page-1#comment-38590 AmyT Thu, 18 Oct 2007 16:37:04 +0000 http://diabetesmine.dreamhosters.com/2007/09/11/lettuce-hope-but-not-too-much/#comment-38590 Tricia, I never presume to know all this stuff on my own. The "negativity" you sense here came from Dr. Jay Sklyer and other experts. Just passing on their very real skepticism that lettuce will bring a cure any time in the next century. Tricia,
I never presume to know all this stuff on my own. The “negativity” you sense here came from Dr. Jay Sklyer and other experts. Just passing on their very real skepticism that lettuce will bring a cure any time in the next century.

]]> By: tricia http://www.diabetesmine.com/2007/09/lettuce-hope-bu.html/comment-page-1#comment-38589 tricia Thu, 18 Oct 2007 15:59:48 +0000 http://diabetesmine.dreamhosters.com/2007/09/11/lettuce-hope-but-not-too-much/#comment-38589 You need to really know what you are talking about with respect to the lettuce cure...it's an infused insulin gene in the cytoplast of the lettucs that doesn't break open until it reaches the gut. At that point it is absorbed into the bloodstream and settles in the pancrease igniting adult stem cells to turn into beta cells that produce insulin. Please be careful to not dash the hopes of literally millions with your negativity. It seems that you do not have all the facts to make such comments. You need to really know what you are talking about with respect to the lettuce cure…it’s an infused insulin gene in the cytoplast of the lettucs that doesn’t break open until it reaches the gut. At that point it is absorbed into the bloodstream and settles in the pancrease igniting adult stem cells to turn into beta cells that produce insulin. Please be careful to not dash the hopes of literally millions with your negativity. It seems that you do not have all the facts to make such comments.

]]> By: robin http://www.diabetesmine.com/2007/09/lettuce-hope-bu.html/comment-page-1#comment-38588 robin Tue, 25 Sep 2007 22:30:37 +0000 http://diabetesmine.dreamhosters.com/2007/09/11/lettuce-hope-but-not-too-much/#comment-38588 It is my opinion that researchers are very close to a cure for diabetes, however, I believe that health insurance companies would lose a large chunk of their profit driven revenue if a cure should be found. Does anyone really think the insurance companies really want a cure for a disease which is one of the most profitable? It is my opinion that researchers are very close to a cure for diabetes, however, I believe that health insurance companies would lose a large chunk of their profit driven revenue if a cure should be found. Does anyone really think the insurance companies really want a cure for a disease which is one of the most profitable?

]]> By: gretchen http://www.diabetesmine.com/2007/09/lettuce-hope-bu.html/comment-page-1#comment-38587 gretchen Fri, 14 Sep 2007 19:53:16 +0000 http://diabetesmine.dreamhosters.com/2007/09/11/lettuce-hope-but-not-too-much/#comment-38587 If anyone is interested in the science behind the Great Lettuce Caper, I've blogged about it here: <a target="_blank" href="http://www.healthcentral.com/diabetes/c/5068/11951/lettuce-diabetes/" rel="nofollow">http://www.healthcentral.com/diabetes/c/5068/11951/lettuce-diabetes/</a> If anyone is interested in the science behind the Great Lettuce Caper, I’ve blogged about it here: http://www.healthcentral.com/diabetes/c/5068/11951/lettuce-diabetes/

]]> By: Sunil S Chiplunkar http://www.diabetesmine.com/2007/09/lettuce-hope-bu.html/comment-page-1#comment-38586 Sunil S Chiplunkar Fri, 14 Sep 2007 10:27:40 +0000 http://diabetesmine.dreamhosters.com/2007/09/11/lettuce-hope-but-not-too-much/#comment-38586 I wonder why is there no focus on glucagon in the battle against diabetes? I wonder why is there no focus on glucagon in the battle against diabetes?

]]> By: Albert http://www.diabetesmine.com/2007/09/lettuce-hope-bu.html/comment-page-1#comment-38585 Albert Wed, 12 Sep 2007 05:10:13 +0000 http://diabetesmine.dreamhosters.com/2007/09/11/lettuce-hope-but-not-too-much/#comment-38585 I'm glad Sue was able to present a contrasting perspective on comparing the latest lettuce developments with Dr. Faustman's research. I would be concerned if all of the funding and effort into Dr. Faustman's research only produced "a lot of PR but not a lot of data." There's definitely a lot of hope being invested in it. I’m glad Sue was able to present a contrasting perspective on comparing the latest lettuce developments with Dr. Faustman’s research.

I would be concerned if all of the funding and effort into Dr. Faustman’s research only produced “a lot of PR but not a lot of data.” There’s definitely a lot of hope being invested in it.

]]> By: AmyT http://www.diabetesmine.com/2007/09/lettuce-hope-bu.html/comment-page-1#comment-38584 AmyT Wed, 12 Sep 2007 04:07:08 +0000 http://diabetesmine.dreamhosters.com/2007/09/11/lettuce-hope-but-not-too-much/#comment-38584 Thanks for the input, Sue. I'm just reporting what the experts are telling me. As usual, the experts disagree. Thanks for the input, Sue. I’m just reporting what the experts are telling me. As usual, the experts disagree.

]]>