13 Responses

  1. Manny Hernandez
    Manny Hernandez September 11, 2007 at 8:35 am | | Reply

    I tried to get in touch with Dr. Daniell with no luck.

    In the meantime, I’ve posted this video on YouTube, which I am hoping to get into the YouChoose ’08 initiative, to see what US presidential candidates have to say:

  2. Sue Root
    Sue Root September 11, 2007 at 5:50 pm | | Reply

    I’d like to comment on the statements below that were written in the previous posting comparing the recent “lettuce cure” and Dr. Faustman’s research:

    “Essentially what Daniell is proposing is not far from Denise Faustman’s research — altering the immune system to prevent the attack on the pancreas. But even she has delayed her human trials because the complicated methodology for lab analysis of results isn’t quite ready yet, according to Skyler.
    “(Denise Faustman) has gotten a lot of PR but not a lot of data.”

    The lettuce research isn’t close to Dr. Faustman’s research. Most importantly, Faustman reversed and cured diabetes in mice with “end-stage” disease not prevention or early onset like the lettuce research and the other 200+ research projects that have been done in the past. Faustman’s treatment is based on 2 identical defects of the immune system found in the mice and humans. Too many times, scientists show a successful effect in prediabetic or early onset diseased mice with a treatment and jump to human trials calling it the first potential cure. Dr. Faustman has done her experiments on 100′s of mice (not just 20 or 30) and most improtantly knows why and how the treatment eliminated the autoreactive T cells selectively and has tons of data to back this up in mice (which has been confirmed by multiple labs )and in human blood samples from her pre-clinical work that has been ongoing for several years.
    The pace of Dr. Faustman’s research to human trials has solely been dependent on funding. The research has done nothing but progress to developing the first bioassay for autoimmunity and reliable automation process for the human trials. Dr. Fausmtan’s research is by far the most data collected to support the possiblity of reversing and curing diabetes in humans who already live with the disease. To say that she has gotten alot of PR without any data is not true. She has collected over 1200 blood samples from humans of all ages and stages of diabetes from a few months diagnosed to over 50 years living with the disease. Stating that the recent lettuce research is like Dr. Faustman’s most innovative human trial project for type I diabetes yet, just gives the reader false information.

  3. AmyT
    AmyT September 11, 2007 at 9:07 pm | | Reply

    Thanks for the input, Sue. I’m just reporting what the experts are telling me. As usual, the experts disagree.

  4. Albert
    Albert September 11, 2007 at 10:10 pm | | Reply

    I’m glad Sue was able to present a contrasting perspective on comparing the latest lettuce developments with Dr. Faustman’s research.

    I would be concerned if all of the funding and effort into Dr. Faustman’s research only produced “a lot of PR but not a lot of data.” There’s definitely a lot of hope being invested in it.

  5. Sunil S Chiplunkar
    Sunil S Chiplunkar September 14, 2007 at 3:27 am | | Reply

    I wonder why is there no focus on glucagon in the battle against diabetes?

  6. gretchen
    gretchen September 14, 2007 at 12:53 pm | | Reply

    If anyone is interested in the science behind the Great Lettuce Caper, I’ve blogged about it here:

  7. robin
    robin September 25, 2007 at 3:30 pm | | Reply

    It is my opinion that researchers are very close to a cure for diabetes, however, I believe that health insurance companies would lose a large chunk of their profit driven revenue if a cure should be found. Does anyone really think the insurance companies really want a cure for a disease which is one of the most profitable?

  8. tricia
    tricia October 18, 2007 at 8:59 am | | Reply

    You need to really know what you are talking about with respect to the lettuce cure…it’s an infused insulin gene in the cytoplast of the lettucs that doesn’t break open until it reaches the gut. At that point it is absorbed into the bloodstream and settles in the pancrease igniting adult stem cells to turn into beta cells that produce insulin. Please be careful to not dash the hopes of literally millions with your negativity. It seems that you do not have all the facts to make such comments.

  9. AmyT
    AmyT October 18, 2007 at 9:37 am | | Reply

    I never presume to know all this stuff on my own. The “negativity” you sense here came from Dr. Jay Sklyer and other experts. Just passing on their very real skepticism that lettuce will bring a cure any time in the next century.

  10. mel
    mel November 6, 2007 at 3:58 pm | | Reply

    what about the chili peper extract cure from Canada last December? Any new info on that? I think Diabetes will be cured by something very simple- something right under our noses

  11. Ken
    Ken August 28, 2008 at 3:33 am | | Reply

    Since diabetes is an autoimmune disease any agent that acts to produce insulin producing cells in the pancreas will also be fought off by the body which will probably produce unanticipated side effects. Were probably still a long way off on this one.

  12. Greg
    Greg September 27, 2008 at 3:54 pm | | Reply

    As I looked into the reports I at first was skeptical. I don’t care to have another delivery method for insulin since (as another comment pointed out) insulin is not a cure, but is only a temporary relief. But upon closer look, this technique with Lettuce is not to deliver insulin but is to stop the destruction of beta cells. See the following article:

    In this article you see that what is happening is that they are using a trick to get the intestinal cells to take up intact proinsulin, not insulin itself. This proinsulin does not affect the blood sugar; instead it results in a significant increase in compounds that suppress immune responses. This causes a reduction in the immune system attack on the beta cells. Over time the body replaces beta cells and they are not destroyed, so this is a potential cure of type 1 diabetes. I would be very excited to take part in a trial to see if this has benefit. It may be that this pill would have to be taken the rest of my life to continue to prevent the destruction of beta cells, but that is better than taking insulin (and symlin) through pumps and injections to treat some of the issues of not having beta cells.


  13. Molly Garsa
    Molly Garsa September 10, 2013 at 11:22 am | | Reply

    The reason that this research, which has proven to work, will never make it is because drug lobbyisits don’t want anyone capitalizing on the billion dollar diabetic drug industry.

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