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	<title>Comments on: Onward and Upward</title>
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	<link>http://www.diabetesmine.com/2007/04/onward_and_upwa.html</link>
	<description>A gold mine of straight talk and encouragement for people living with diabetes</description>
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		<title>By: Axel</title>
		<link>http://www.diabetesmine.com/2007/04/onward_and_upwa.html/comment-page-1#comment-37301</link>
		<dc:creator>Axel</dc:creator>
		<pubDate>Thu, 12 Apr 2007 17:33:05 +0000</pubDate>
		<guid isPermaLink="false">http://diabetesmine.dreamhosters.com/2007/04/11/onward-and-upward/#comment-37301</guid>
		<description>Congratulation again for your blog and for the Open Letter.

You did it great.

Let&#039;s continue, it is worth while.
</description>
		<content:encoded><![CDATA[<p>Congratulation again for your blog and for the Open Letter.</p>
<p>You did it great.</p>
<p>Let&#8217;s continue, it is worth while.</p>
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	<item>
		<title>By: Arron</title>
		<link>http://www.diabetesmine.com/2007/04/onward_and_upwa.html/comment-page-1#comment-37300</link>
		<dc:creator>Arron</dc:creator>
		<pubDate>Thu, 12 Apr 2007 16:27:38 +0000</pubDate>
		<guid isPermaLink="false">http://diabetesmine.dreamhosters.com/2007/04/11/onward-and-upward/#comment-37300</guid>
		<description>Another Type1 here...

I&#039;m curious Amy, have you heard anything in response from any of the pump manufacters?  In the end, they are the ones who need to be on board with the idea.

In regards to the comments posted by M, I hear what you are saying about the technically challanged having possible problems with all the bells and whistles...but there are already pumps on the market if you require a &quot;simple&quot; pump.

Heck, I think a good first step would be to have software to wirelessly communicate with your ipod/pda/nintendo ds so you could use them as a glorified interface for your pump.

I know my Minimed can transmit info over bluetooth/rf already...why couldn&#039;t we see  future products that would let me keep the pump in my pocket and deal with a software suite on my ipod/pda/nintendo DS?
</description>
		<content:encoded><![CDATA[<p>Another Type1 here&#8230;</p>
<p>I&#8217;m curious Amy, have you heard anything in response from any of the pump manufacters?  In the end, they are the ones who need to be on board with the idea.</p>
<p>In regards to the comments posted by M, I hear what you are saying about the technically challanged having possible problems with all the bells and whistles&#8230;but there are already pumps on the market if you require a &#8220;simple&#8221; pump.</p>
<p>Heck, I think a good first step would be to have software to wirelessly communicate with your ipod/pda/nintendo ds so you could use them as a glorified interface for your pump.</p>
<p>I know my Minimed can transmit info over bluetooth/rf already&#8230;why couldn&#8217;t we see  future products that would let me keep the pump in my pocket and deal with a software suite on my ipod/pda/nintendo DS?</p>
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	<item>
		<title>By: a</title>
		<link>http://www.diabetesmine.com/2007/04/onward_and_upwa.html/comment-page-1#comment-37299</link>
		<dc:creator>a</dc:creator>
		<pubDate>Thu, 12 Apr 2007 14:20:54 +0000</pubDate>
		<guid isPermaLink="false">http://diabetesmine.dreamhosters.com/2007/04/11/onward-and-upward/#comment-37299</guid>
		<description>I am a insulin pumping diabetic who works in usability and user experience design for a living.  While I agree with amy&#039;s gripes, there are so many issues that make good design in medical devices a challenge that don&#039;t apply to the consumer electronics world.  For instance, unlike an ipod, an insulin pump or glucometer MUST be able to be understood by both a child and an elderly person.  Does my grandma know how to use an iPod?  No, she doesn&#039;t have to but if she was a diabetic, it would be a must for her to know how to use her glucometer. I can say from experience, that is it pretty rare that you will create something that both the young and old will understand and welcome with open arms.

Another issue is the time involved in training.  My diabetes educator trained me on my animas 1250 in less than an hour - there isn&#039;t anything I can&#039;t do on it.  I am on my third iPod, work in human computer interaction and i STILL don&#039;t understand everything my iPod can do.  Now I understand that we aren&#039;t suggesting that an insulin pump becomes an iPod, but for me, the simplicity and ease of use that I find my insulin pump already has (and I would say I am pretty critical, since it is my job), would outweigh any desire I would have for a slicker looking device.
</description>
		<content:encoded><![CDATA[<p>I am a insulin pumping diabetic who works in usability and user experience design for a living.  While I agree with amy&#8217;s gripes, there are so many issues that make good design in medical devices a challenge that don&#8217;t apply to the consumer electronics world.  For instance, unlike an ipod, an insulin pump or glucometer MUST be able to be understood by both a child and an elderly person.  Does my grandma know how to use an iPod?  No, she doesn&#8217;t have to but if she was a diabetic, it would be a must for her to know how to use her glucometer. I can say from experience, that is it pretty rare that you will create something that both the young and old will understand and welcome with open arms.</p>
<p>Another issue is the time involved in training.  My diabetes educator trained me on my animas 1250 in less than an hour &#8211; there isn&#8217;t anything I can&#8217;t do on it.  I am on my third iPod, work in human computer interaction and i STILL don&#8217;t understand everything my iPod can do.  Now I understand that we aren&#8217;t suggesting that an insulin pump becomes an iPod, but for me, the simplicity and ease of use that I find my insulin pump already has (and I would say I am pretty critical, since it is my job), would outweigh any desire I would have for a slicker looking device.</p>
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		<title>By: M</title>
		<link>http://www.diabetesmine.com/2007/04/onward_and_upwa.html/comment-page-1#comment-37298</link>
		<dc:creator>M</dc:creator>
		<pubDate>Thu, 12 Apr 2007 13:13:49 +0000</pubDate>
		<guid isPermaLink="false">http://diabetesmine.dreamhosters.com/2007/04/11/onward-and-upward/#comment-37298</guid>
		<description>GREAT stuff! I love how you&#039;ve got so much attention over this.
Perhaps what truly matters is that our things work, but style matters too. Having stylish pumps, CGMS, and even insulin pens for those of us without all that cool technology (me included *sigh*), help us to feel like we&#039;re not broken people. We don&#039;t need anything else to make us feel like the odd one out!
I&#039;ll have a small racy-dark-red pump please (with FM radio), a zebra striped CGMS that I can send pxt from, and a matching handbag and scarf. *grin*
</description>
		<content:encoded><![CDATA[<p>GREAT stuff! I love how you&#8217;ve got so much attention over this.<br />
Perhaps what truly matters is that our things work, but style matters too. Having stylish pumps, CGMS, and even insulin pens for those of us without all that cool technology (me included *sigh*), help us to feel like we&#8217;re not broken people. We don&#8217;t need anything else to make us feel like the odd one out!<br />
I&#8217;ll have a small racy-dark-red pump please (with FM radio), a zebra striped CGMS that I can send pxt from, and a matching handbag and scarf. *grin*</p>
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		<title>By: Phil</title>
		<link>http://www.diabetesmine.com/2007/04/onward_and_upwa.html/comment-page-1#comment-37297</link>
		<dc:creator>Phil</dc:creator>
		<pubDate>Thu, 12 Apr 2007 13:11:09 +0000</pubDate>
		<guid isPermaLink="false">http://diabetesmine.dreamhosters.com/2007/04/11/onward-and-upward/#comment-37297</guid>
		<description>Looks like your open letter was picked up on by someone at the Guardian newspaper over here in blighty.

&lt;a target=&quot;_blank&quot; href=&quot;http://technology.guardian.co.uk/weekly/story/0,,2054392,00.html&quot; rel=&quot;nofollow&quot;&gt;http://technology.guardian.co.uk/weekly/story/0,,2054392,00.html&lt;/a&gt;

Phil
</description>
		<content:encoded><![CDATA[<p>Looks like your open letter was picked up on by someone at the Guardian newspaper over here in blighty.</p>
<p><a target="_blank" href="http://technology.guardian.co.uk/weekly/story/0,,2054392,00.html" rel="nofollow">http://technology.guardian.co.uk/weekly/story/0,,2054392,00.html</a></p>
<p>Phil</p>
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	<item>
		<title>By: Wendy Morgan</title>
		<link>http://www.diabetesmine.com/2007/04/onward_and_upwa.html/comment-page-1#comment-37296</link>
		<dc:creator>Wendy Morgan</dc:creator>
		<pubDate>Thu, 12 Apr 2007 01:46:23 +0000</pubDate>
		<guid isPermaLink="false">http://diabetesmine.dreamhosters.com/2007/04/11/onward-and-upward/#comment-37296</guid>
		<description>Hey there!

I just wanted to drop you a line and say I got my Minimed Minilink plugged in!  Yea, CGM/pump all in one.  I find this very different from my Freestyle Navigator experience, so I&#039;m doing more blogging about that.

I sent back my first Minimed Pump upgrade to the 722 becuase the &quot;smoke&quot; color looked so...institutional. I got the clear instead! Fashion First!

Thanks for keeping interesting topics on your page.  You make me think!

W
</description>
		<content:encoded><![CDATA[<p>Hey there!</p>
<p>I just wanted to drop you a line and say I got my Minimed Minilink plugged in!  Yea, CGM/pump all in one.  I find this very different from my Freestyle Navigator experience, so I&#8217;m doing more blogging about that.</p>
<p>I sent back my first Minimed Pump upgrade to the 722 becuase the &#8220;smoke&#8221; color looked so&#8230;institutional. I got the clear instead! Fashion First!</p>
<p>Thanks for keeping interesting topics on your page.  You make me think!</p>
<p>W</p>
]]></content:encoded>
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	<item>
		<title>By: BillyWarhol</title>
		<link>http://www.diabetesmine.com/2007/04/onward_and_upwa.html/comment-page-1#comment-37295</link>
		<dc:creator>BillyWarhol</dc:creator>
		<pubDate>Wed, 11 Apr 2007 19:13:02 +0000</pubDate>
		<guid isPermaLink="false">http://diabetesmine.dreamhosters.com/2007/04/11/onward-and-upward/#comment-37295</guid>
		<description>Amy I am really disappointed U are not getting this Incredible News on Steps towards a CURE out for Diabetes??

Ferget about Steve Jobs + Mike &quot;I throw c0ol Web2.0 Parties&quot; Arrington -neither of whom is a Diabetic + Post this little Good NEWS for Diabetics that was on CNN!!

sheeeesh - i Hope U get yer Free iPod!  + go to a Blogger Party*



I may have Great News for U Amy &amp; all the Diabetics*

We may not need Steve Jobs Apple or the Oranges i practised on with a Needle 35 Years ago*

Stem cells could spell end for diabetes jabs
By DANIEL MARTIN - More by this author » Last updated at 00:20am on 11th April 2007

Comments Comments
Hopes have been raised of a new treatment to free thousands of diabetes sufferers from the burden of daily insulin injections.

Scientists revealed findings of a study which shows that 15 young patients with type one diabetes overcame their dependence on insulin after being treated with their own stem cells.

scroll down for more
insulin

A new scientific breakthrough could spell the end of insulin injections

The researchers say it could herald the start of a revolution in treating type one diabetes, which affects 300,000 patients in Britain.

Type one diabetics have to regularly inject themselves with the hormone insulin to control their blood sugar levels.

The new research has emerged a month after it was revealed that the number of British children under the age of five who had developed type one diabetes had risen fivefold in the past 20 years.

A team of US and Brazilian scientists gave the patients powerful drugs to suppress their immune systems followed by injections of stem cells drawn from their own blood.

After treatment, 14 of the 15 were able to put away their injection pens after losing their insulin dependence.

And so far, one patient has been free of insulin dependency for 35 months.

Study leader Dr Julio Voltarelli from the University of Sao Paolo said he had rushed out his findings because of the positive results.

He said: &quot;Very encouraging results were obtained in a small number of patients with early-onset disease.

&quot;Ninety-three per cent of patients achieved different periods of insulin dependence and treatment-related toxicity was low, with no mortality.&quot;

Type one diabetes is caused by insulin-producing beta cells in the pancreas being destroyed by the patient&#039;s own immune system.

Stem cells are immature cells that can develop to become a range of different adult cells.

In the latest trial, patients&#039; immune systems were suppressed using powerful drugs - to eliminate the white blood cells that were attacking the pancreas.

The patient was then injected with a chemical which loosened stem cells from their bone marrow. These were filtered out, collected and later injected back into the patient&#039;s bloodstream.

Some of the 14 patients responded more quickly than others, according to the study published in the Journal of the American Medical Association.

Researchers believe the stem cells developed into new white blood cells which did not attack the pancreatic beta cells.

But they admit there are other possible interpretations - the stem cells could have developed into new beta cells in the pancreas. Or something might have happened to stop the existing beta cells being destroyed.

The study only included a small number of patients between 14 and 31, and did not monitor their progress for very long.

Because of the nature of the study, it is not known if further stem cell injections would be required at a later date.

And unlike most medical trials there was no comparison with patients left untreated or only given drugs to suppress their immune system.

Malcolm Alison, professor of stem cell biology at the Queen Mary School of Medicine and Dentistry in London, said: &quot;In principle this is a cure because these people developed long-term control of their glucose levels.

&quot;But these patients haven&#039;t been followed up long enough, so we cannot yet be sure.&quot;

Dr Ian Frame, research manager at Diabetes UK, said: &quot;This is interesting new research that demonstrates that there may have been a substantial improvement in beta cell fundtion. However we would wish to avoid false hope based on the very preliminary nature of these results.

&quot;This study had a very small number of participants and importantly did not include a randomised control group for comparison of results.

&quot;Also, as the researchers say, those who took part have not been sufficiently followed up to find out whether or not the improvements have continued.

&quot;All these issues need to be addressed through more research before there are any conclusive findings in this area.&quot;

There have been several pointers towards this latest discovery.

Studies have alreday shown that bone marrow transplants given to cancer patients also seemed to reverse certain auto-immune disease such as type one diabetes. Bone marrow is full of stem cells.

Later it was found that treating patients with stem cells from their own blood could benefit individuals with a range of auto-immune diseases such as rheumatoid arthritis and Chron&#039;s disease


</description>
		<content:encoded><![CDATA[<p>Amy I am really disappointed U are not getting this Incredible News on Steps towards a CURE out for Diabetes??</p>
<p>Ferget about Steve Jobs + Mike &#8220;I throw c0ol Web2.0 Parties&#8221; Arrington -neither of whom is a Diabetic + Post this little Good NEWS for Diabetics that was on CNN!!</p>
<p>sheeeesh &#8211; i Hope U get yer Free iPod!  + go to a Blogger Party*</p>
<p>I may have Great News for U Amy &#038; all the Diabetics*</p>
<p>We may not need Steve Jobs Apple or the Oranges i practised on with a Needle 35 Years ago*</p>
<p>Stem cells could spell end for diabetes jabs<br />
By DANIEL MARTIN &#8211; More by this author » Last updated at 00:20am on 11th April 2007</p>
<p>Comments Comments<br />
Hopes have been raised of a new treatment to free thousands of diabetes sufferers from the burden of daily insulin injections.</p>
<p>Scientists revealed findings of a study which shows that 15 young patients with type one diabetes overcame their dependence on insulin after being treated with their own stem cells.</p>
<p>scroll down for more<br />
insulin</p>
<p>A new scientific breakthrough could spell the end of insulin injections</p>
<p>The researchers say it could herald the start of a revolution in treating type one diabetes, which affects 300,000 patients in Britain.</p>
<p>Type one diabetics have to regularly inject themselves with the hormone insulin to control their blood sugar levels.</p>
<p>The new research has emerged a month after it was revealed that the number of British children under the age of five who had developed type one diabetes had risen fivefold in the past 20 years.</p>
<p>A team of US and Brazilian scientists gave the patients powerful drugs to suppress their immune systems followed by injections of stem cells drawn from their own blood.</p>
<p>After treatment, 14 of the 15 were able to put away their injection pens after losing their insulin dependence.</p>
<p>And so far, one patient has been free of insulin dependency for 35 months.</p>
<p>Study leader Dr Julio Voltarelli from the University of Sao Paolo said he had rushed out his findings because of the positive results.</p>
<p>He said: &#8220;Very encouraging results were obtained in a small number of patients with early-onset disease.</p>
<p>&#8220;Ninety-three per cent of patients achieved different periods of insulin dependence and treatment-related toxicity was low, with no mortality.&#8221;</p>
<p>Type one diabetes is caused by insulin-producing beta cells in the pancreas being destroyed by the patient&#8217;s own immune system.</p>
<p>Stem cells are immature cells that can develop to become a range of different adult cells.</p>
<p>In the latest trial, patients&#8217; immune systems were suppressed using powerful drugs &#8211; to eliminate the white blood cells that were attacking the pancreas.</p>
<p>The patient was then injected with a chemical which loosened stem cells from their bone marrow. These were filtered out, collected and later injected back into the patient&#8217;s bloodstream.</p>
<p>Some of the 14 patients responded more quickly than others, according to the study published in the Journal of the American Medical Association.</p>
<p>Researchers believe the stem cells developed into new white blood cells which did not attack the pancreatic beta cells.</p>
<p>But they admit there are other possible interpretations &#8211; the stem cells could have developed into new beta cells in the pancreas. Or something might have happened to stop the existing beta cells being destroyed.</p>
<p>The study only included a small number of patients between 14 and 31, and did not monitor their progress for very long.</p>
<p>Because of the nature of the study, it is not known if further stem cell injections would be required at a later date.</p>
<p>And unlike most medical trials there was no comparison with patients left untreated or only given drugs to suppress their immune system.</p>
<p>Malcolm Alison, professor of stem cell biology at the Queen Mary School of Medicine and Dentistry in London, said: &#8220;In principle this is a cure because these people developed long-term control of their glucose levels.</p>
<p>&#8220;But these patients haven&#8217;t been followed up long enough, so we cannot yet be sure.&#8221;</p>
<p>Dr Ian Frame, research manager at Diabetes UK, said: &#8220;This is interesting new research that demonstrates that there may have been a substantial improvement in beta cell fundtion. However we would wish to avoid false hope based on the very preliminary nature of these results.</p>
<p>&#8220;This study had a very small number of participants and importantly did not include a randomised control group for comparison of results.</p>
<p>&#8220;Also, as the researchers say, those who took part have not been sufficiently followed up to find out whether or not the improvements have continued.</p>
<p>&#8220;All these issues need to be addressed through more research before there are any conclusive findings in this area.&#8221;</p>
<p>There have been several pointers towards this latest discovery.</p>
<p>Studies have alreday shown that bone marrow transplants given to cancer patients also seemed to reverse certain auto-immune disease such as type one diabetes. Bone marrow is full of stem cells.</p>
<p>Later it was found that treating patients with stem cells from their own blood could benefit individuals with a range of auto-immune diseases such as rheumatoid arthritis and Chron&#8217;s disease</p>
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		<title>By: Ray</title>
		<link>http://www.diabetesmine.com/2007/04/onward_and_upwa.html/comment-page-1#comment-37294</link>
		<dc:creator>Ray</dc:creator>
		<pubDate>Wed, 11 Apr 2007 18:57:19 +0000</pubDate>
		<guid isPermaLink="false">http://diabetesmine.dreamhosters.com/2007/04/11/onward-and-upward/#comment-37294</guid>
		<description>Forget equipment redesign, get our government to fund stem cell research! Looks like the Brits have a cure for type 1. Go to www.timesonline.co.uk and look for the headline about diabetics cured with stem-cell research.
</description>
		<content:encoded><![CDATA[<p>Forget equipment redesign, get our government to fund stem cell research! Looks like the Brits have a cure for type 1. Go to <a href="http://www.timesonline.co.uk" rel="nofollow">http://www.timesonline.co.uk</a> and look for the headline about diabetics cured with stem-cell research.</p>
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		<title>By: Laura</title>
		<link>http://www.diabetesmine.com/2007/04/onward_and_upwa.html/comment-page-1#comment-37293</link>
		<dc:creator>Laura</dc:creator>
		<pubDate>Wed, 11 Apr 2007 18:29:04 +0000</pubDate>
		<guid isPermaLink="false">http://diabetesmine.dreamhosters.com/2007/04/11/onward-and-upward/#comment-37293</guid>
		<description>Great Job Amy!  I&#039;m glad we have you on our side!   I&#039;m all for smaller and more discreet ways to handle MY personal &quot;thing&quot;.  More options with devices gives those with diabetes a choice and, therefore, not feeling so left out of technology stepping forward, as it does so often.
</description>
		<content:encoded><![CDATA[<p>Great Job Amy!  I&#8217;m glad we have you on our side!   I&#8217;m all for smaller and more discreet ways to handle MY personal &#8220;thing&#8221;.  More options with devices gives those with diabetes a choice and, therefore, not feeling so left out of technology stepping forward, as it does so often.</p>
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		<title>By: Tesney</title>
		<link>http://www.diabetesmine.com/2007/04/onward_and_upwa.html/comment-page-1#comment-37291</link>
		<dc:creator>Tesney</dc:creator>
		<pubDate>Wed, 11 Apr 2007 18:02:25 +0000</pubDate>
		<guid isPermaLink="false">http://diabetesmine.dreamhosters.com/2007/04/11/onward-and-upward/#comment-37291</guid>
		<description>Just now catching up on yesterday&#039;s post and all of the comments.  I&#039;m 100% with you on calling for the technical world to help out with the design of medical equipment.  I feel like I couldn&#039;t live without my pump but I&#039;m tired of finding creative ways to disquise it when I want to wear form-fitting clothing or having to take it off all together when I wear a swimsuit.  Kudos, Amy, for raising awareness...looks like it&#039;s working!
</description>
		<content:encoded><![CDATA[<p>Just now catching up on yesterday&#8217;s post and all of the comments.  I&#8217;m 100% with you on calling for the technical world to help out with the design of medical equipment.  I feel like I couldn&#8217;t live without my pump but I&#8217;m tired of finding creative ways to disquise it when I want to wear form-fitting clothing or having to take it off all together when I wear a swimsuit.  Kudos, Amy, for raising awareness&#8230;looks like it&#8217;s working!</p>
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