<?xml version="1.0" encoding="UTF-8"?><rss version="2.0"
	xmlns:content="http://purl.org/rss/1.0/modules/content/"
	xmlns:dc="http://purl.org/dc/elements/1.1/"
	xmlns:atom="http://www.w3.org/2005/Atom"
	xmlns:sy="http://purl.org/rss/1.0/modules/syndication/"
		>
<channel>
	<title>Comments on: Holy @#$! Amazing Stories, Vol. 4: Quest for Animal Insulin</title>
	<atom:link href="http://www.diabetesmine.com/2006/02/holy_amazing_st.html/feed" rel="self" type="application/rss+xml" />
	<link>http://www.diabetesmine.com/2006/02/holy_amazing_st.html</link>
	<description>A gold mine of straight talk and encouragement for people living with diabetes</description>
	<lastBuildDate>Mon, 13 Feb 2012 01:28:10 +0000</lastBuildDate>
	<sy:updatePeriod>hourly</sy:updatePeriod>
	<sy:updateFrequency>1</sy:updateFrequency>
	<generator>http://wordpress.org/?v=</generator>
<xhtml:meta xmlns:xhtml="http://www.w3.org/1999/xhtml" name="robots" content="noindex" />
	<item>
		<title>By: Dave</title>
		<link>http://www.diabetesmine.com/2006/02/holy_amazing_st.html/comment-page-1#comment-35073</link>
		<dc:creator>Dave</dc:creator>
		<pubDate>Mon, 10 Jul 2006 18:52:53 +0000</pubDate>
		<guid isPermaLink="false">http://diabetesmine.dreamhosters.com/2006/02/05/holy-amazing-stories-vol-4-quest-for-animal-insulin/#comment-35073</guid>
		<description>I have been on Humalog and UltraLente for over 12 years. I found out I was no longer on UltraLente when I tried to refill my prescription last month and was told I couldn&#039;t.  When I asked why they told me that Lilly no longer made it.

I&#039;ve been diabetic for 48 years with no complications.  I went on the Humulin insulins because I had very little or no warning of impending lows.

I&#039;ve always worked very physical jobs, ie hanging drywall, lugging beef and humping boxs of beef, that sort of thing.

I&#039;m not as young now and have a desk job that entails about 25% physical the rest sitting on my duff.

Now that all that is over with My question is this; has anyone else lost their drive to exercise or do pretty much anything?  I always was very physical my whole life up until the last 2 or 3 years and it seems to be getting progressively worse.  It seems I can&#039;t force myself to do anything as far as working out.  I&#039;m always tired can&#039;t get enough sleep.  I never used to be this way and it is depressing.

Anyone out there know what&#039;s going on with me?  Insulin maybe?
</description>
		<content:encoded><![CDATA[<p>I have been on Humalog and UltraLente for over 12 years. I found out I was no longer on UltraLente when I tried to refill my prescription last month and was told I couldn&#8217;t.  When I asked why they told me that Lilly no longer made it.</p>
<p>I&#8217;ve been diabetic for 48 years with no complications.  I went on the Humulin insulins because I had very little or no warning of impending lows.</p>
<p>I&#8217;ve always worked very physical jobs, ie hanging drywall, lugging beef and humping boxs of beef, that sort of thing.</p>
<p>I&#8217;m not as young now and have a desk job that entails about 25% physical the rest sitting on my duff.</p>
<p>Now that all that is over with My question is this; has anyone else lost their drive to exercise or do pretty much anything?  I always was very physical my whole life up until the last 2 or 3 years and it seems to be getting progressively worse.  It seems I can&#8217;t force myself to do anything as far as working out.  I&#8217;m always tired can&#8217;t get enough sleep.  I never used to be this way and it is depressing.</p>
<p>Anyone out there know what&#8217;s going on with me?  Insulin maybe?</p>
]]></content:encoded>
	</item>
	<item>
		<title>By: KathDewhirst</title>
		<link>http://www.diabetesmine.com/2006/02/holy_amazing_st.html/comment-page-1#comment-35072</link>
		<dc:creator>KathDewhirst</dc:creator>
		<pubDate>Tue, 21 Feb 2006 20:14:48 +0000</pubDate>
		<guid isPermaLink="false">http://diabetesmine.dreamhosters.com/2006/02/05/holy-amazing-stories-vol-4-quest-for-animal-insulin/#comment-35072</guid>
		<description>I have been using Novorapid and Lantus for 2 years which gave me a better quality of life. But have started feeling generally unwell an hour or so after injections, having palpitations and hypo symptoms when I am not any where near hypo. I believe that the GM Insulin may be to blame and am going to try animal insulin. I am a little worried that this GM insulin has not been put through rigourous tests and we are in fact guinea pigs after all.
</description>
		<content:encoded><![CDATA[<p>I have been using Novorapid and Lantus for 2 years which gave me a better quality of life. But have started feeling generally unwell an hour or so after injections, having palpitations and hypo symptoms when I am not any where near hypo. I believe that the GM Insulin may be to blame and am going to try animal insulin. I am a little worried that this GM insulin has not been put through rigourous tests and we are in fact guinea pigs after all.</p>
]]></content:encoded>
	</item>
	<item>
		<title>By: Kirk</title>
		<link>http://www.diabetesmine.com/2006/02/holy_amazing_st.html/comment-page-1#comment-35071</link>
		<dc:creator>Kirk</dc:creator>
		<pubDate>Wed, 08 Feb 2006 16:11:38 +0000</pubDate>
		<guid isPermaLink="false">http://diabetesmine.dreamhosters.com/2006/02/05/holy-amazing-stories-vol-4-quest-for-animal-insulin/#comment-35071</guid>
		<description>Bill:

When I went on Novolog and Lantus after a bunch of years oif Type 1 I found my hypoglycemic symptoms were differnt.  I had to re-learn what it meant to be low.  A little focus made the transition successful.
</description>
		<content:encoded><![CDATA[<p>Bill:</p>
<p>When I went on Novolog and Lantus after a bunch of years oif Type 1 I found my hypoglycemic symptoms were differnt.  I had to re-learn what it meant to be low.  A little focus made the transition successful.</p>
]]></content:encoded>
	</item>
	<item>
		<title>By: Bill the diabetesdoc</title>
		<link>http://www.diabetesmine.com/2006/02/holy_amazing_st.html/comment-page-1#comment-35070</link>
		<dc:creator>Bill the diabetesdoc</dc:creator>
		<pubDate>Wed, 08 Feb 2006 11:04:01 +0000</pubDate>
		<guid isPermaLink="false">http://diabetesmine.dreamhosters.com/2006/02/05/holy-amazing-stories-vol-4-quest-for-animal-insulin/#comment-35070</guid>
		<description>Jim&#039;s story is only testimonial evidence: one person&#039;s experience and nothing more.

There&#039;s been a lot of hot air, and little evidence, that synthetic-human or analog insulins per se are hypoglycemogenic (I think that&#039;s a new word, BTW!)

Much more likely, other lifestyle changes were involved in explaining the hypos, or perhaps simple lack of understanding of how to initiate a basal/bolus program.

Until/unless there are randomized clinical trials of animal-source vs synthetic-human or analog insulins, the controversy will continue, fueled by personal frustrations and without scientific rigor. And such studies are extremely unlikely to be funded by industry or demanded by Health Authorities: there simply isn&#039;t enough data to date to support the need for such studies.

PS: I&#039;m on Lantus/Novolog basal/bolus program, and would recommend such a program (or a pump) to anyone who&#039;s truly motivated to make lifestyle changes using an extremely complex program.

PPS to Jim: It&#039;s unclear whether you were under the care of a diabetes team. If you didn&#039;t have interactions with a CDE dietitian to learn carb counting, and a CDE nurse educator, and daily contact with them to review your blood sugar levels vs activity level, meals, and stress levels, it&#039;s no surprise that you find yourself in this pickle.
</description>
		<content:encoded><![CDATA[<p>Jim&#8217;s story is only testimonial evidence: one person&#8217;s experience and nothing more.</p>
<p>There&#8217;s been a lot of hot air, and little evidence, that synthetic-human or analog insulins per se are hypoglycemogenic (I think that&#8217;s a new word, BTW!)</p>
<p>Much more likely, other lifestyle changes were involved in explaining the hypos, or perhaps simple lack of understanding of how to initiate a basal/bolus program.</p>
<p>Until/unless there are randomized clinical trials of animal-source vs synthetic-human or analog insulins, the controversy will continue, fueled by personal frustrations and without scientific rigor. And such studies are extremely unlikely to be funded by industry or demanded by Health Authorities: there simply isn&#8217;t enough data to date to support the need for such studies.</p>
<p>PS: I&#8217;m on Lantus/Novolog basal/bolus program, and would recommend such a program (or a pump) to anyone who&#8217;s truly motivated to make lifestyle changes using an extremely complex program.</p>
<p>PPS to Jim: It&#8217;s unclear whether you were under the care of a diabetes team. If you didn&#8217;t have interactions with a CDE dietitian to learn carb counting, and a CDE nurse educator, and daily contact with them to review your blood sugar levels vs activity level, meals, and stress levels, it&#8217;s no surprise that you find yourself in this pickle.</p>
]]></content:encoded>
	</item>
	<item>
		<title>By: Kirk</title>
		<link>http://www.diabetesmine.com/2006/02/holy_amazing_st.html/comment-page-1#comment-35069</link>
		<dc:creator>Kirk</dc:creator>
		<pubDate>Wed, 08 Feb 2006 02:49:08 +0000</pubDate>
		<guid isPermaLink="false">http://diabetesmine.dreamhosters.com/2006/02/05/holy-amazing-stories-vol-4-quest-for-animal-insulin/#comment-35069</guid>
		<description>Sorry Megan I mis-understood.  ;-)

Kirk
</description>
		<content:encoded><![CDATA[<p>Sorry Megan I mis-understood.  <img src='https://www.diabetesmine.com/wp-includes/images/smilies/icon_wink.gif' alt=';-)' class='wp-smiley' /> </p>
<p>Kirk</p>
]]></content:encoded>
	</item>
	<item>
		<title>By: Megan</title>
		<link>http://www.diabetesmine.com/2006/02/holy_amazing_st.html/comment-page-1#comment-35068</link>
		<dc:creator>Megan</dc:creator>
		<pubDate>Tue, 07 Feb 2006 23:52:57 +0000</pubDate>
		<guid isPermaLink="false">http://diabetesmine.dreamhosters.com/2006/02/05/holy-amazing-stories-vol-4-quest-for-animal-insulin/#comment-35068</guid>
		<description>Kirk, I did not quote that statistic.  I was quoting a person from a different comment and disagreeing with him.  I agree with you.  I love my Lantus and Humalog.
</description>
		<content:encoded><![CDATA[<p>Kirk, I did not quote that statistic.  I was quoting a person from a different comment and disagreeing with him.  I agree with you.  I love my Lantus and Humalog.</p>
]]></content:encoded>
	</item>
	<item>
		<title>By: Kirk</title>
		<link>http://www.diabetesmine.com/2006/02/holy_amazing_st.html/comment-page-1#comment-35067</link>
		<dc:creator>Kirk</dc:creator>
		<pubDate>Tue, 07 Feb 2006 21:58:23 +0000</pubDate>
		<guid isPermaLink="false">http://diabetesmine.dreamhosters.com/2006/02/05/holy-amazing-stories-vol-4-quest-for-animal-insulin/#comment-35067</guid>
		<description>Megan:

Please foward the studies showing an increase by 40% of comps ?  I read alot and have never seen this information.  I am amazed such a thing has occured and I haven&#039;t seen the publication.

I love Lantus and Novolog, tehy beat the heck out of NPH and R (used them for over 35 years)

Also Megan you&#039;ll find if you survive without comps for 30 years you will probably never develop them (Joslin)

Kirk
</description>
		<content:encoded><![CDATA[<p>Megan:</p>
<p>Please foward the studies showing an increase by 40% of comps ?  I read alot and have never seen this information.  I am amazed such a thing has occured and I haven&#8217;t seen the publication.</p>
<p>I love Lantus and Novolog, tehy beat the heck out of NPH and R (used them for over 35 years)</p>
<p>Also Megan you&#8217;ll find if you survive without comps for 30 years you will probably never develop them (Joslin)</p>
<p>Kirk</p>
]]></content:encoded>
	</item>
	<item>
		<title>By: Megan</title>
		<link>http://www.diabetesmine.com/2006/02/holy_amazing_st.html/comment-page-1#comment-35066</link>
		<dc:creator>Megan</dc:creator>
		<pubDate>Mon, 06 Feb 2006 19:54:09 +0000</pubDate>
		<guid isPermaLink="false">http://diabetesmine.dreamhosters.com/2006/02/05/holy-amazing-stories-vol-4-quest-for-animal-insulin/#comment-35066</guid>
		<description>In the middle part of my previous comment, I was trying to quote a different comment.  I thought it would show up in italics, but I guess I did something wrong.
</description>
		<content:encoded><![CDATA[<p>In the middle part of my previous comment, I was trying to quote a different comment.  I thought it would show up in italics, but I guess I did something wrong.</p>
]]></content:encoded>
	</item>
	<item>
		<title>By: Megan</title>
		<link>http://www.diabetesmine.com/2006/02/holy_amazing_st.html/comment-page-1#comment-35065</link>
		<dc:creator>Megan</dc:creator>
		<pubDate>Mon, 06 Feb 2006 19:52:47 +0000</pubDate>
		<guid isPermaLink="false">http://diabetesmine.dreamhosters.com/2006/02/05/holy-amazing-stories-vol-4-quest-for-animal-insulin/#comment-35065</guid>
		<description>The chances of hypoglycemia unawareness go up the longer you have diabetes.  I wonder if Jim considered that his increased hypoglycemia unawareness is merely a result of having diabetes longer than he did when on pork/beef.

&quot;Personally I would not touch the GM mould that is called insulin.
Since the introduction of synthetic insulins the complications and death rates have gone up by 40%.
There are many people that can not use the synthetic insulins and are denied the choice of using the animal insulins.
On pork and Beef insulin you do not have fits and seizures for a start.&quot;

Many, many things are GM.  And it&#039;s not necessarily a bad thing.  I&#039;m willing to bet that complications increased (if they did, which I&#039;m not sure I believe in and of itself) as a result of people with diabetes living longer.  Plain and simple- people live longer, more people have complications.

As far as &quot;fits and seizures&quot; are concerned, I suspect you are referring to hypoglycemia, which is a risk with any insulin treatment.

</description>
		<content:encoded><![CDATA[<p>The chances of hypoglycemia unawareness go up the longer you have diabetes.  I wonder if Jim considered that his increased hypoglycemia unawareness is merely a result of having diabetes longer than he did when on pork/beef.</p>
<p>&#8220;Personally I would not touch the GM mould that is called insulin.<br />
Since the introduction of synthetic insulins the complications and death rates have gone up by 40%.<br />
There are many people that can not use the synthetic insulins and are denied the choice of using the animal insulins.<br />
On pork and Beef insulin you do not have fits and seizures for a start.&#8221;</p>
<p>Many, many things are GM.  And it&#8217;s not necessarily a bad thing.  I&#8217;m willing to bet that complications increased (if they did, which I&#8217;m not sure I believe in and of itself) as a result of people with diabetes living longer.  Plain and simple- people live longer, more people have complications.</p>
<p>As far as &#8220;fits and seizures&#8221; are concerned, I suspect you are referring to hypoglycemia, which is a risk with any insulin treatment.</p>
]]></content:encoded>
	</item>
	<item>
		<title>By: Kirk</title>
		<link>http://www.diabetesmine.com/2006/02/holy_amazing_st.html/comment-page-1#comment-35064</link>
		<dc:creator>Kirk</dc:creator>
		<pubDate>Mon, 06 Feb 2006 19:43:32 +0000</pubDate>
		<guid isPermaLink="false">http://diabetesmine.dreamhosters.com/2006/02/05/holy-amazing-stories-vol-4-quest-for-animal-insulin/#comment-35064</guid>
		<description>As I tightened my control over the decades I experienced more lows.  Tighter control means more work.  As we all know an A1C of 10 is not good.  Some people can and do live long and healthy lives with elevated A1Cs,

I would like to see the studies indicating a 40% increase in death and complications after the new insulins were introduced; I find that claim hard to believe.

Unfortunately sometimes people do not want to accept change; that is their choice in an ever changing world.

The technological changes and changes in insulins have had a very positive impact on my life.
</description>
		<content:encoded><![CDATA[<p>As I tightened my control over the decades I experienced more lows.  Tighter control means more work.  As we all know an A1C of 10 is not good.  Some people can and do live long and healthy lives with elevated A1Cs,</p>
<p>I would like to see the studies indicating a 40% increase in death and complications after the new insulins were introduced; I find that claim hard to believe.</p>
<p>Unfortunately sometimes people do not want to accept change; that is their choice in an ever changing world.</p>
<p>The technological changes and changes in insulins have had a very positive impact on my life.</p>
]]></content:encoded>
	</item>
</channel>
</rss>

