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	<title>Comments on: Farewell to Needles?? Breathe Deep&#8230;</title>
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	<link>http://www.diabetesmine.com/2005/12/farewell_to_nee.html</link>
	<description>A gold mine of straight talk and encouragement for people living with diabetes</description>
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		<title>By: exuberaN</title>
		<link>http://www.diabetesmine.com/2005/12/farewell_to_nee.html/comment-page-1#comment-34904</link>
		<dc:creator>exuberaN</dc:creator>
		<pubDate>Tue, 31 Jan 2006 16:47:22 +0000</pubDate>
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		<description>Pfizer now have the FDA Approval for the first inhaled insulin named Exubera. If you like smoke or resumes smoking you can&#039;t take Exubera. If you have chronic lung disease such as asthma, you should not take Exubera.
</description>
		<content:encoded><![CDATA[<p>Pfizer now have the FDA Approval for the first inhaled insulin named Exubera. If you like smoke or resumes smoking you can&#8217;t take Exubera. If you have chronic lung disease such as asthma, you should not take Exubera.</p>
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		<title>By: Amir</title>
		<link>http://www.diabetesmine.com/2005/12/farewell_to_nee.html/comment-page-1#comment-34903</link>
		<dc:creator>Amir</dc:creator>
		<pubDate>Tue, 20 Dec 2005 06:43:29 +0000</pubDate>
		<guid isPermaLink="false">http://diabetesmine.dreamhosters.com/2005/12/09/farewell-to-needles-breathe-deep/#comment-34903</guid>
		<description>Any advancement in medicine is possible by some brave people just like you. This could be a very important and helpful way for using Insulin esp. in developing country. My mother who takes Insulin injection (She still has to use old fashioned thick needles and she hates it every time, it&#039;s painful) has to take a cool box everywhere she goes and put her insulin inside with some ice and injecting is painful. I can&#039;t send her new syringes from Sweden to her because Insulins are different and I can&#039;t send her the insulin every now and then so these inhaling Insulins could be a miracle for her. I hope she would be alive until 2008 and can use this kind of Insulin at last for once.
</description>
		<content:encoded><![CDATA[<p>Any advancement in medicine is possible by some brave people just like you. This could be a very important and helpful way for using Insulin esp. in developing country. My mother who takes Insulin injection (She still has to use old fashioned thick needles and she hates it every time, it&#8217;s painful) has to take a cool box everywhere she goes and put her insulin inside with some ice and injecting is painful. I can&#8217;t send her new syringes from Sweden to her because Insulins are different and I can&#8217;t send her the insulin every now and then so these inhaling Insulins could be a miracle for her. I hope she would be alive until 2008 and can use this kind of Insulin at last for once.</p>
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	<item>
		<title>By: In the Pipeline</title>
		<link>http://www.diabetesmine.com/2005/12/farewell_to_nee.html/comment-page-1#comment-34905</link>
		<dc:creator>In the Pipeline</dc:creator>
		<pubDate>Wed, 14 Dec 2005 15:32:01 +0000</pubDate>
		<guid isPermaLink="false">http://diabetesmine.dreamhosters.com/2005/12/09/farewell-to-needles-breathe-deep/#comment-34905</guid>
		<description>&lt;strong&gt;Grand Rounds&lt;/strong&gt;

Welcome to the latest iteration of Grand Rounds. On behalf of the greedy rapacious pharmaceutical industry, I&#039;m glad to be hosting this week. Unfortunately for everyone, the research end of the G.R.P.I. is not immersed in the ceaseless flow of...
</description>
		<content:encoded><![CDATA[<p><strong>Grand Rounds</strong></p>
<p>Welcome to the latest iteration of Grand Rounds. On behalf of the greedy rapacious pharmaceutical industry, I&#8217;m glad to be hosting this week. Unfortunately for everyone, the research end of the G.R.P.I. is not immersed in the ceaseless flow of&#8230;</p>
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	<item>
		<title>By: CardioNP</title>
		<link>http://www.diabetesmine.com/2005/12/farewell_to_nee.html/comment-page-1#comment-34902</link>
		<dc:creator>CardioNP</dc:creator>
		<pubDate>Wed, 14 Dec 2005 03:36:11 +0000</pubDate>
		<guid isPermaLink="false">http://diabetesmine.dreamhosters.com/2005/12/09/farewell-to-needles-breathe-deep/#comment-34902</guid>
		<description>When I worked in primary care I had 2 patients on my panel who participated in inhaled insulin trials.  Not sure which company it was as I was their PCP and not involved in the trial at all.  Neither patient had adequately controlled sugars and I needed to tweak their oral meds.  Neither patient was very compliant with diet/exercise, so can&#039;t be sure it was the inhaled insulin that was the problem.  But overall, I was not impressed with inhaled insulin based on these 2 patients.
</description>
		<content:encoded><![CDATA[<p>When I worked in primary care I had 2 patients on my panel who participated in inhaled insulin trials.  Not sure which company it was as I was their PCP and not involved in the trial at all.  Neither patient had adequately controlled sugars and I needed to tweak their oral meds.  Neither patient was very compliant with diet/exercise, so can&#8217;t be sure it was the inhaled insulin that was the problem.  But overall, I was not impressed with inhaled insulin based on these 2 patients.</p>
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		<title>By: Will</title>
		<link>http://www.diabetesmine.com/2005/12/farewell_to_nee.html/comment-page-1#comment-34901</link>
		<dc:creator>Will</dc:creator>
		<pubDate>Mon, 12 Dec 2005 05:05:07 +0000</pubDate>
		<guid isPermaLink="false">http://diabetesmine.dreamhosters.com/2005/12/09/farewell-to-needles-breathe-deep/#comment-34901</guid>
		<description>Have you considered that they probably won&#039;t let you write ANYTHING about your experience?  Be sure to find out about that.
</description>
		<content:encoded><![CDATA[<p>Have you considered that they probably won&#8217;t let you write ANYTHING about your experience?  Be sure to find out about that.</p>
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		<title>By: type1emt</title>
		<link>http://www.diabetesmine.com/2005/12/farewell_to_nee.html/comment-page-1#comment-34900</link>
		<dc:creator>type1emt</dc:creator>
		<pubDate>Sun, 11 Dec 2005 20:13:36 +0000</pubDate>
		<guid isPermaLink="false">http://diabetesmine.dreamhosters.com/2005/12/09/farewell-to-needles-breathe-deep/#comment-34900</guid>
		<description>not me- even if I weren&#039;t on a pump. I have asthma, and with my luck I&#039;d be the one to get lung damage. I&#039;m sure you&#039;ll make a wise decision and if the study has any neg. effects, you can always drop out.
good luck!
</description>
		<content:encoded><![CDATA[<p>not me- even if I weren&#8217;t on a pump. I have asthma, and with my luck I&#8217;d be the one to get lung damage. I&#8217;m sure you&#8217;ll make a wise decision and if the study has any neg. effects, you can always drop out.<br />
good luck!</p>
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		<title>By: Florian Menninger, Jr</title>
		<link>http://www.diabetesmine.com/2005/12/farewell_to_nee.html/comment-page-1#comment-34899</link>
		<dc:creator>Florian Menninger, Jr</dc:creator>
		<pubDate>Sun, 11 Dec 2005 14:15:25 +0000</pubDate>
		<guid isPermaLink="false">http://diabetesmine.dreamhosters.com/2005/12/09/farewell-to-needles-breathe-deep/#comment-34899</guid>
		<description>I interviewed at a place that was recruiting patients for the Clinical Trial by Mannkind. I decided not to go ahead with it after thinking about how I feel with a bad cold and lung congestion. Would I really be able to inhale the insulin dose when I was congested and felt like someone was sitting on my chest or would I resort to a syringe for an injection? The purpose of the study is to see how the therapy effects the lungs.  A lot depends on the quality of the dry insulin powder. Did you know that Biocon is one of the largest producers of Insulin?
I have been a practicing Type 1 for 38 years and I have injected a lot of insulin and tried a lot of different regimens. I am now trying to convince myself to try an Insulin Pump. Good luck if you decide to join the Clinical Trial.






</description>
		<content:encoded><![CDATA[<p>I interviewed at a place that was recruiting patients for the Clinical Trial by Mannkind. I decided not to go ahead with it after thinking about how I feel with a bad cold and lung congestion. Would I really be able to inhale the insulin dose when I was congested and felt like someone was sitting on my chest or would I resort to a syringe for an injection? The purpose of the study is to see how the therapy effects the lungs.  A lot depends on the quality of the dry insulin powder. Did you know that Biocon is one of the largest producers of Insulin?<br />
I have been a practicing Type 1 for 38 years and I have injected a lot of insulin and tried a lot of different regimens. I am now trying to convince myself to try an Insulin Pump. Good luck if you decide to join the Clinical Trial.</p>
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	<item>
		<title>By: elizabeth</title>
		<link>http://www.diabetesmine.com/2005/12/farewell_to_nee.html/comment-page-1#comment-34898</link>
		<dc:creator>elizabeth</dc:creator>
		<pubDate>Sun, 11 Dec 2005 10:32:02 +0000</pubDate>
		<guid isPermaLink="false">http://diabetesmine.dreamhosters.com/2005/12/09/farewell-to-needles-breathe-deep/#comment-34898</guid>
		<description>If there is one thing you don&#039;t have to worry about is the huge amount of support you would get from all your fellow d-bloggers...

I remember when my daughter was 4 months old and my doctor and I discussed my joining an islet transplantation trial.  It was terrible...while I wanted to do it, the timing was all wrong.  Because there were some risks with the surgery and post-surgical uptake  - we decided my participating was unfair to this little person we had just brought into the world!

I believe your partner and your children need to voice concerns and agree to the study...after that, you just have to follow your gut instinct.
</description>
		<content:encoded><![CDATA[<p>If there is one thing you don&#8217;t have to worry about is the huge amount of support you would get from all your fellow d-bloggers&#8230;</p>
<p>I remember when my daughter was 4 months old and my doctor and I discussed my joining an islet transplantation trial.  It was terrible&#8230;while I wanted to do it, the timing was all wrong.  Because there were some risks with the surgery and post-surgical uptake  &#8211; we decided my participating was unfair to this little person we had just brought into the world!</p>
<p>I believe your partner and your children need to voice concerns and agree to the study&#8230;after that, you just have to follow your gut instinct.</p>
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		<title>By: Breanna</title>
		<link>http://www.diabetesmine.com/2005/12/farewell_to_nee.html/comment-page-1#comment-34897</link>
		<dc:creator>Breanna</dc:creator>
		<pubDate>Sat, 10 Dec 2005 06:51:23 +0000</pubDate>
		<guid isPermaLink="false">http://diabetesmine.dreamhosters.com/2005/12/09/farewell-to-needles-breathe-deep/#comment-34897</guid>
		<description>Hi.
I know its hard for us to realize the truth about studies and new drugs. And its sad to know that there is no real way to know how safe any new drug on the market is going to affect different populations. Sometimes we can only benefit from experimentation, and at one time or another, we will have to be a subject, to help benefit mankind. After all, we are benefiting from  others who have come before us, who have participated in studies, or made an sacrifice. Now its our turn to contribute for those who will come after us.
</description>
		<content:encoded><![CDATA[<p>Hi.<br />
I know its hard for us to realize the truth about studies and new drugs. And its sad to know that there is no real way to know how safe any new drug on the market is going to affect different populations. Sometimes we can only benefit from experimentation, and at one time or another, we will have to be a subject, to help benefit mankind. After all, we are benefiting from  others who have come before us, who have participated in studies, or made an sacrifice. Now its our turn to contribute for those who will come after us.</p>
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	<item>
		<title>By: PrintCrafter</title>
		<link>http://www.diabetesmine.com/2005/12/farewell_to_nee.html/comment-page-1#comment-34896</link>
		<dc:creator>PrintCrafter</dc:creator>
		<pubDate>Sat, 10 Dec 2005 02:31:04 +0000</pubDate>
		<guid isPermaLink="false">http://diabetesmine.dreamhosters.com/2005/12/09/farewell-to-needles-breathe-deep/#comment-34896</guid>
		<description>Hmmmm...that&#039;s a tough one. I for one LOVE my pump. No way I&#039;d trade pumping for huffing. On the other hand it is fun to be on the cutting edge. As you haven&#039;t made the pump leap yet, maybe this is a better route for you?

It&#039;s not like you&#039;re going to be the first person on the planet to inhale insulin, so I think the risk side of the equation is low.

If it feels right (as a therpy) to you I think you should go for it.
</description>
		<content:encoded><![CDATA[<p>Hmmmm&#8230;that&#8217;s a tough one. I for one LOVE my pump. No way I&#8217;d trade pumping for huffing. On the other hand it is fun to be on the cutting edge. As you haven&#8217;t made the pump leap yet, maybe this is a better route for you?</p>
<p>It&#8217;s not like you&#8217;re going to be the first person on the planet to inhale insulin, so I think the risk side of the equation is low.</p>
<p>If it feels right (as a therpy) to you I think you should go for it.</p>
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