Comments on: Closing the Loop http://www.diabetesmine.com/2005/06/closing_the_loo.html A gold mine of straight talk and encouragement for people living with diabetes Thu, 18 Mar 2010 02:09:44 +0000 http://wordpress.org/?v=2.9.1 hourly 1 By: Stayci http://www.diabetesmine.com/2005/06/closing_the_loo.html/comment-page-1#comment-253837 Stayci Mon, 02 Mar 2009 04:16:56 +0000 http://diabetesmine.dreamhosters.com/2005/06/21/closing-the-loop/#comment-253837 Just as a note, not sure if anyone will read this post since it is four years old. But, i'm an electrical engineering student doing a research project on this exact thing. I am actually able to do this without logarithms, using what is called fuzzy logic. Not sure if I will ever come up with a marketable product, let alone a finished product, but there is hope!! Just as a note, not sure if anyone will read this post since it is four years old. But, i’m an electrical engineering student doing a research project on this exact thing. I am actually able to do this without logarithms, using what is called fuzzy logic. Not sure if I will ever come up with a marketable product, let alone a finished product, but there is hope!!

]]> By: Jason http://www.diabetesmine.com/2005/06/closing_the_loo.html/comment-page-1#comment-53653 Jason Sat, 23 Aug 2008 07:06:31 +0000 http://diabetesmine.dreamhosters.com/2005/06/21/closing-the-loop/#comment-53653 are you kidding me? There will be no cure, to much money to be made. Please tell me you are smarter than that. I've been a diabetic for over 25 years and wear pump. I also wear the sencers and my spelling is poor. They will only create ways to make us spend more and more money. are you kidding me? There will be no cure, to much money to be made. Please tell me you are smarter than that. I’ve been a diabetic for over 25 years and wear pump. I also wear the sencers and my spelling is poor. They will only create ways to make us spend more and more money.

]]> By: jessica http://www.diabetesmine.com/2005/06/closing_the_loo.html/comment-page-1#comment-43192 jessica Mon, 23 Jun 2008 13:11:15 +0000 http://diabetesmine.dreamhosters.com/2005/06/21/closing-the-loop/#comment-43192 they are looking for a cure why do you think they take part in walks to cure it. I have had diabetes 6 years now and taken part in all of them. there is hope never say that there isn't because they are trying. OK jessica they are looking for a cure why do you think they take part in walks to cure it. I have had diabetes 6 years now and taken part in all of them. there is hope never say that there isn’t because they are trying. OK

jessica

]]> By: LARRY GOLDSTEIN http://www.diabetesmine.com/2005/06/closing_the_loo.html/comment-page-1#comment-34286 LARRY GOLDSTEIN Fri, 23 Dec 2005 10:56:02 +0000 http://diabetesmine.dreamhosters.com/2005/06/21/closing-the-loop/#comment-34286 My daughter has has had type 1 diabetes since age 9.She is now 22. The reason progress for a cure or effective treatment is so slow is simple.There is no money in cures only treatments. No one is looking for a cure because that would damage the bottom line. My daughter has has had type 1 diabetes since age 9.She is now 22.

The reason progress for a cure or effective treatment is so slow is simple.There is no money in cures only treatments. No one is looking for a cure because that would damage the bottom line.

]]> By: Kevin McMahon http://www.diabetesmine.com/2005/06/closing_the_loo.html/comment-page-1#comment-34285 Kevin McMahon Fri, 08 Jul 2005 13:50:39 +0000 http://diabetesmine.dreamhosters.com/2005/06/21/closing-the-loop/#comment-34285 Great diabetes blog! Of all the blogs I've read recently this is the first one that I've been compelled to share some relevant information. An alternative approach to continuous glucose is in the research phase of development and involves putting together several existing technologies in a system which will ask patients to test at the 8 to 12 most pivotal times in the day. It's a similar problem of developing and testing the accuracy of predictive algorithms that consider the patient's history and data inputs but one that comes with significantly reduced risk. Great diabetes blog! Of all the blogs I’ve read recently this is the first one that I’ve been compelled to share some relevant information.

An alternative approach to continuous glucose is in the research phase of development and involves putting together several existing technologies in a system which will ask patients to test at the 8 to 12 most pivotal times in the day. It’s a similar problem of developing and testing the accuracy of predictive algorithms that consider the patient’s history and data inputs but one that comes with significantly reduced risk.

]]> By: Kathleen Weaver http://www.diabetesmine.com/2005/06/closing_the_loo.html/comment-page-1#comment-34284 Kathleen Weaver Sat, 25 Jun 2005 03:22:27 +0000 http://diabetesmine.dreamhosters.com/2005/06/21/closing-the-loop/#comment-34284 The closed loop system isn't going to happen until there is a viable, reliable continous blood glucose monitor system. Therasense has been "close" for the past 4 years, but has not been for sale yet. Minimed marketed but didn't sell their Guardian system, but I haven't seen anything from internet posts on this session on it. Not from you, not from Medline, or any of the other reports. I'm not sure you can find it from their website anymore, I've looked but not digged. By marketed I mean, announced on websites and at pumpers meetings it was coming. I've met a few guinea pigs (subjects of clinical trials) on the internet for some of the other systems and they claim that they aren't reliable. So don't count on 5 years. Maybe 5 years on the continuous glucose monitor, maybe not. The closed loop system isn’t going to happen until there is a viable, reliable continous blood glucose monitor system.

Therasense has been “close” for the past 4 years, but has not been for sale yet.

Minimed marketed but didn’t sell their Guardian system, but I haven’t seen anything from internet posts on this session on it. Not from you, not from Medline, or any of the other reports.
I’m not sure you can find it from their website anymore, I’ve looked but not digged.

By marketed I mean, announced on websites and at pumpers meetings it was coming.

I’ve met a few guinea pigs (subjects of clinical trials) on the internet for some of the other systems and they claim that
they aren’t reliable.

So don’t count on 5 years. Maybe 5 years on the continuous glucose monitor, maybe not.

]]> By: DensityDuck http://www.diabetesmine.com/2005/06/closing_the_loo.html/comment-page-1#comment-34283 DensityDuck Wed, 22 Jun 2005 20:03:38 +0000 http://diabetesmine.dreamhosters.com/2005/06/21/closing-the-loop/#comment-34283 Low BG would be handled the way it gets handled in anyone else--you eat something. People with functional pancreas don't get lows, they get hungry. That said, I would certainly expect this closed-loop system to follow a paradigm other than "basal rate = x.xx units per hour from now until Doomsday". It would adjust the basal up or down dependent on the current BG reading and its trend (up, down, level.) In other words, it would work in exactly the same manner as a "natural" pancreas; and nobody worries that a natural pancreas is going to suddenly go berserk and start spewing out insulin. Low BG would be handled the way it gets handled in anyone else–you eat something. People with functional pancreas don’t get lows, they get hungry.

That said, I would certainly expect this closed-loop system to follow a paradigm other than “basal rate = x.xx units per hour from now until Doomsday”. It would adjust the basal up or down dependent on the current BG reading and its trend (up, down, level.) In other words, it would work in exactly the same manner as a “natural” pancreas; and nobody worries that a natural pancreas is going to suddenly go berserk and start spewing out insulin.

]]> By: Robert http://www.diabetesmine.com/2005/06/closing_the_loo.html/comment-page-1#comment-34282 Robert Wed, 22 Jun 2005 18:05:48 +0000 http://diabetesmine.dreamhosters.com/2005/06/21/closing-the-loop/#comment-34282 I would think that any system that gets approved would need to have double or triple redundancy on the BG side of things which may make it less appealing. I also am not sure on how it would handle lows - would it require the person to also carry an internal supply of glucagon? I would think that any system that gets approved would need to have double or triple redundancy on the BG side of things which may make it less appealing. I also am not sure on how it would handle lows – would it require the person to also carry an internal supply of glucagon?

]]> By: Alexis http://www.diabetesmine.com/2005/06/closing_the_loo.html/comment-page-1#comment-34281 Alexis Wed, 22 Jun 2005 13:35:06 +0000 http://diabetesmine.dreamhosters.com/2005/06/21/closing-the-loop/#comment-34281 How would such a system would be able to deal with intense exercise? If your bs were to suddenly drop would you still have to worry about carrying around glucose? I suppose that really wouldn't be all that bad, instead of diabetics we would simply be hypoglycemics. How would such a system would be able to deal with intense exercise? If your bs were to suddenly drop would you still have to worry about carrying around glucose? I suppose that really wouldn’t be all that bad, instead of diabetics we would simply be hypoglycemics.

]]> By: Dr. Roosevelt http://www.diabetesmine.com/2005/06/closing_the_loo.html/comment-page-1#comment-34280 Dr. Roosevelt Tue, 21 Jun 2005 15:19:15 +0000 http://diabetesmine.dreamhosters.com/2005/06/21/closing-the-loop/#comment-34280 I've been told that a closed-loop system would be available in the "near future" for over 20 years. So don't get your hopes up too high that it will be ready by 2008. I’ve been told that a closed-loop system would be available in the “near future” for over 20 years. So don’t get your hopes up too high that it will be ready by 2008.

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